Deadline reported the reboot earned 108.3 million dollars worldwide over its opening weekend, a total that places it ahead of the prior live-action Resident Evil films during their initial domestic and international runs.
Background and creative team
The film, co-written by Zach Cregger and screenwriter Shay Hatten, stars Austin Abrams alongside Zach Cherry, Kali Reis, Paul Walter Hauser, and Jonno Wilson.
It follows a tense, single-night story set across Raccoon City as a medical courier named Bryan transports a critical package to the city hospital amid an outbreak.
The movie is in theaters now.
Box office and franchise comparison
Deadline's figures show the reboot topped the opening weekend totals of previous entries and has already surpassed the full theatrical runs of two earlier franchise films.
The 2002 Resident Evil opened at and ultimately grossed 102.9 million dollars worldwide in its full run, while 2021's Resident Evil: Welcome to Raccoon City collected 41.9 million dollars globally.
By contrast, Resident Evil 2016's The Final Chapter remains the highest-grossing live-action entry in the series with a global total of about 312 million dollars.
A milestone for Zach Cregger
The film marks a career-high box office result for director Zach Cregger.
It exceeds the reported worldwide gross of approximately 70 million dollars for his previous horror feature, Weapons.
Industry tracking shows the new Resident Evil is now one of the more commercially successful modern adaptations of a video game property in theatrical release.
Why it matters
The performance underscores continued market appetite for established IP and horror reboots in cinemas.
It also reinforces the ongoing cultural influence of the Resident Evil franchise across media, from Capcom's decades-long game series to film adaptations and related merchandise.
For fans following both games and cinema, the film's commercial start will be a point of attention as studios and developers evaluate cross-media strategies.
For further reading, industry outlets and box office trackers continue to update weekend-to-weekend grosses and longer-term totals as the film completes its theatrical run.